Genome stability versus transcript diversity
نویسندگان
چکیده
منابع مشابه
The Role of MDM2 in Promoting Genome Stability versus Instability
In cancer, the mouse double minute 2 (MDM2) is an oncoprotein that contributes to the promotion of cell growth, survival, invasion, and therapeutic resistance. The impact of MDM2 on cell survival versus cell death is complex and dependent on levels of MDM2 isoforms, p53 status, and cellular context. Extensive investigations have demonstrated that MDM2 protein-protein interactions with p53 and o...
متن کاملExtraction of Transcript Diversity from Scientific Literature
Transcript diversity generated by alternative splicing and associated mechanisms contributes heavily to the functional complexity of biological systems. The numerous examples of the mechanisms and functional implications of these events are scattered throughout the scientific literature. Thus, it is crucial to have a tool that can automatically extract the relevant facts and collect them in a k...
متن کاملThermoregulation of Escherichia coli hchA transcript stability.
The conserved chaperone Hsp31 of Escherichia coli is transcribed at low temperatures by sigma(S) and repressed by H-NS, whereas at high temperature, transcription is by sigma70 independently of both sigma(S) and H-NS. Here we present evidence for an additional, novel, temperature-dependent control of Hsp31 expression by increased transcript stability.
متن کاملEnergy diversity brings stability.
Energy diversity brings stability W hen I pull up to a gas-station pump, I have three choices: regular, premium, or something in between. I make the obvious choice and fill up with the cheapest option (while I wonder who uses those even more expensive fuels). It is the same scenario whether I'm in State College, Pa., or Los Angeles. All across the U.S., we have a transportation infrastructure b...
متن کاملWheat Landrace Genome Diversity
Understanding the genomic complexity of bread wheat (Triticum aestivum L.) is a cornerstone in the quest to unravel the processes of domestication and the following adaptation of domesticated wheat to a wide variety of environments across the globe. Additionally, it is of importance for future improvement of the crop, particularly in the light of climate change. Focusing on the adaptation after...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: DNA Repair
سال: 2016
ISSN: 1568-7864
DOI: 10.1016/j.dnarep.2016.05.010